Comparison Overview
The Brooks Glycerin 22 is the latest evolution of the Glycerin 21 line. We recommend the Glycerin 21 for most runners.
How the Brooks Glycerin 21 and Brooks Glycerin 22 differ
The Brooks Glycerin 21 and the Brooks Glycerin 22 are both long run shoes from Brooks, which makes this a classic same-line comparison: same design language, similar fit philosophy, but meaningful changes in feel and intended use.
Where they actually differ: the Brooks Glycerin 22 comes in roughly 1.5 oz lighter (10.6 oz vs 9.1 oz), which becomes noticeable on faster turnover and longer efforts; the Brooks Glycerin 21 rides on the taller stack (38mm/28mm vs 32mm/22mm), giving it more under-foot cushioning at the cost of a slightly less stable platform; and the Brooks Glycerin 21 is $50 cheaper at MSRP ($160 vs $210).
Head-to-Head Comparison
| Feature | Brooks Glycerin 21 | Brooks Glycerin 22 |
|---|---|---|
| Brand | Brooks | Brooks |
| Model | Glycerin 21 | Glycerin 22 |
| Category | long run | daily trainer |
| Weight | 10.6 oz | 9.1 oz |
| Drop | 10mm | 10mm |
| Price | $160 | $210 |
Frequently Asked Questions
- Which is lighter, the Brooks Glycerin 21 or the Brooks Glycerin 22?
- The Brooks Glycerin 22 is the lighter shoe at 9.1 oz versus 10.6 oz.
- Which costs less?
- The Brooks Glycerin 21 is the more affordable option at $160 compared to $210.
- Can I rotate both shoes in the same training block?
- Yes — many runners pair complementary shoes like these to spread load across different muscles and tendons. Use our rotation planner to build a mileage split that fits your schedule.
Read the full reviews
- Brooks Glycerin 21 — full specs, AI insights, and verdict.
- Brooks Glycerin 22 — full specs, AI insights, and verdict.
- Browse the full running shoe database
- See more shoe comparisons
Not sure which is right for you?
Use our AI-powered shoe finder for personalized recommendations, or build a smart shoe rotation with the rotation planner.